The R2np

A multiple-use solution for implanting Neuropixels 2.0 probes.

The R2np is a metal implantation system for chronic recordings with Neuropixels 2 probes that feature the dovetail caps. It contains micromachined rails to easily attach and secure the probes, similar to the official holders for acute insertions.

The  implant is compatible to our R2Drive ecosystem - it features the same, proven base for stable, long-term chronic implantation and is compatible to the R2Drive holders.

 

Please note that the current design is only compatible to the original IMEC caps, not the slightly larger Sensapex version. 

 

  • A: Compatible with R2Drive im-/ex-plantation holders
  • B: Micromachined dovetail rail for easy connection and precise alignment of the probe
  • C: Two fixation screws for maximal safety and flexibility in locking the probe in place (use one or both)
  • D: R2Drive-compatible base for easy recovery and reuse of the implanted probes

See it in action!

Mounting the probe - The short video on the left shows a naive user's first ever attempt at dismounting a Neuropixels 2.0 probe from the R2np implantation system.  Quick and easy! The first ever mounting (not filmed) took a little longer, but still under 30 seconds. At no point was the probe at risk. And both operations were simple enough to get done with only one hand, leaving the other hand for holding the whole package. In mostwithout fixing the holder to any attachment to have two free hands. 

Implanting the probe - Implantation is standard, with several protocols available (e.g. Vöröslakos et al. 2021, Kinsky et al. 2023). So is explantation, powered by the removable base which can be left onto the animal's skull as the R2np's body and mounted probe are recovered in the stereotax (or manually for the steady hands out there).

Get in on the action!

Interested in being one of the first to use the R2np? As with the R2Drive, we are having a pre-order round to gauge community interest in the R2np. Sign up below for one (or more) of the first 50 implants. Pre-order signup will be open until September 15th (or earlier, if capacity is reached). When you fill in the form, we will reserve the indicated amount of implants for you. When we open the shipping period, we will send you a link for you to create an official quote for the implant

Timeline:

  • September 15: expression of interest signup closes (latest date)
  • September 16-October 5th : pre-orders can be placed
  • late October: expected delivery of the pieces, just in time for your enthusiastic post-SfN experiments!

Get yours:

We still have a few R2np available in our first production run. They will be distributed on a first-come-first serve basis to interested researchers. You can request a quote for them in our quote engine: